Saturday, April 2, 2011

Day 2

Alright, so today was one of the worst day's I have ever experianced, but it didn't start off that way. I woke up feeling good and looking forward to another mostly free day. I started noticing some stomach disscomfort while I was eating breakfast and the omlett didn't taste that well. I think the omlett was fine, I just think it was my tongue. Which by the way is a side effect of Moxifloxacin but more on that latter. The following is kinda gross so don't think don't think I didn't warn you . But soon after breakfast I took a dump for the first time since the day before. Because yesterday was so full of procedures that I just didn't feel like there was enough time. Anyway after the bowel movement I started feeling sick. What I mean by sick is stomach cramps and bouts of nausea. The nausea was followed by chills since I would start sweating during the nausea. Also, all day I was having very frequent bowel movements if you know what I mean. Both these continued throughout the day and would increase and subside significatnly in a somewhat regular pattern. But even then the parts that weren't as bad were pretty bad. I couldn't do anything but lay in my bunk hoping to fall asleep when it wasn't that bad.

During the day I learned that several people got sick last night and they weren't ejected from the study as was said during the orientation. That was comforting to hear considering my situation but I still focused as hard as I could during the nausea. At around 6pm came a the bout like no other, I tried my best but at certain point I knew what was going to happen. I yelled for a trash can because I knew that I wouldn't make it to one then a guy in my room got up and to bring back a trash can He was fast but not fast enough. I cupped my mouth and proceeded to empty my stomach. Luckly it got mostly on myself and my bed. It wasn't going to happen just once but he came back time with trash can for the next one and the next three. It was the defenition of projectile and I have never experainced anything like that. It was quite the commotion but I didn't care because I felt so much better afterwards. They changed my sheets, I took a shower and got some new clothes on. After that was the first time I was able to fall asleep. When I woke up I actually felt hungry and didn't feel any cramps for the first time that day. I forgot to mention that I hardly ate any of my lunch which I was greatful for later. Anyway I was able to eat some of my dinner and I still feel good almost 2 hours later.

Here are my therioes on what is happening. What I hope most is that I am in the placebo who got Moxifloxacin yesterday and it just took a little while to hit especially with my digestive traffic jam. That would mean tomorrow after my dose I wont feel a thing because it would be sugar .

It could also be a virus going around and not related to the study because the previous study of this drug had nobody vomit, but in this one so many people are. Therefore if it is that and the people who experainced it earlier are already over it then I should be completely better soon.

The worst possibilty and the one that will defenatly result in me being expelled is if I am having a bad reaction to the test drug. If it is that and I get dosed tomorrow but somehow don't throw up tomorrow. It doesn't matter because the dosage will increase and I will eventually do it again.

There are a few things that don't make sense if I am reacting to either one of the drugs. Number one is why didn't I react this way yesterday because that is when dosing started and the miligrams have not increased yet. Also why would throughing up at 6pm get ride of symptoms when I was dosed at 8am. At that point it seems the drug would be long gone out of my stomach escpecially since I had no digestinal traffic today. The only one that seems to make sense is the virus one because even after I threw up I still felt a little off and it wasn't until I slept for a few hours that I actually felt good.

All of this is just speculation and wont be know until tomorrow. Its been a while since I ate dinner and still feeling pretty good, not 100% but close. I am sure I will wake up feeling good tomorrow but I just hope that it doesn't repeat because even if I am not kicked out I don't know how I could handle that again.

11:22 and still feeling good and I'll finish my post.   

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